All posts by Nemo

STEM CELLS IN REGENERATIVE MEDICINE – REVIEW

Litercurious Book Review

Stem Cells in Regenerative Medicine by Mike K. S. Chan & Dmitry Klokol
Stem Cells in Regenerative Medicine by Mike K. S. Chan & Dmitry Klokol

Comprehensive review coming soon.

Title Stem Cells in Regenerative Medicine:
Carpe Diem – Carpe Vitam!
Author Mike K. S. Chan, Dmitry Klokol
Publisher Matador (July 31, 2019)
Format Kindle     
Page 551     
Language English     
ASIN # B07VVL2MS7     

Brief Synopsis

Quote: “The goal is to provide a once in a lifetime treatment to correct a specific medical deficit.”

Stem Cells in Regenerative Medicine Carpe Diem-Carpe Vital! (July 31, 2019).

This is a seminal monograph on the subject of the therapeutic application and use of stem cells in “regenerative medicine.” The science described within the pages of this text may be leading edge, but Chan and Klokol have attempted to keep the information accessible to the average reader. However, in some parts the comprehension of the complex science may be challenging. Research scientists and students of medical research may gain the greatest benefits of this work.

The text guides you through the multiple applications of the utilization of Stem Cells and the medical illnesses that may be treated by the use of ‘Xenogeneic Cell Therapy.’ The authors posit the limitations and benefits of the scientific method as it relates explicitly to its use in human subjects. There is a brief description of xenotransplantation in the treatment of cells requiring regenerative assistance in a range of degenerative conditions through cross-species donated cells. Significant importance is placed in the use of cross-species hosts to be Scientific Pathogen Free Animals (SPF – Animals) through the use of ‘Closed Colony’ and proven clinical methods.

Stem Cells in Regenerative Medicine describes the merits, the problemata, and the detailed methodologies of regenerative therapies. The book is replete with beautiful color illustrations that includes the Cell Cycle and the illustrations of the Noble Prize Winner, Günter Blobel, for Physiology or Medicine in 1999. His thesis is on how the distribution mechanism of biological active transport cells migrate, how proteins contain signals inside that direct their location in a destination cell, and how they are transported and where they may migrate to.

I found the Chronology of the development of stem cell research and application to be compelling reading.

Simply the most comprehensive book on the subject of Stem Cells as applied in ‘regenerative medicine,’ and most certainly the best illustrated. The illustrations combined with Chan and Klokol‘s vivid written communication provides you with an invaluable tool in comprehending the ground breaking subject of Stem Cell Therapy.

SEDUCING AND KILLING NAZIS -REVIEW

Litercurious Book Review

Seducing and Killing Nazis:  Sophie Poldermans
Seducing and Killing Nazis by Sophie Poldermans
TitleSeducing and Killing Nazis
AuthorSophie Poldermans
PublisherSWW Press; 1 edition (August 1, 2019)
FormatKindle, Paperback     
Page228     
LanguageEnglish     
ASIN #B07TMRTVBD     

Author’s Bio

Sophie Poldermans is a Dutch, Women’s rights activist and lecturer. She formerly worked at the National Hannie Shaft Foundation (NHSF). It was at the NHSF that she learned of the heroic actions of three Dutch young women and the tragic end of one of them. Poldermans seeks to lift the veil of time off this forgotten tale of daring-do and to remind us of all the sacrifices that many women made during the war.   

Who is the Target Audience?

Seducing and Killing Nazis is foremost a history book but it is also a memorial to Hannie Shaft, one victim of millions. The story is told by her friend Freddie Oversteegen, who is now 90 years old, and her sister Truus. This personal account of the events of World War II will satisfy; students of Military History or those studying the events in Europe during World War II, and those studying the Shoah. It may also be interesting to Feminists and other women. If you enjoy reading about strong characters, especially personal accounts of women in war situations, you could find this book inspirational on many levels.

Synopsis

Seducing and Killing Nazis is monograph by Sophie Poldermans. She introduces us to three ordinary girls who did extraordinary acts during tumultuous times. Of the three main characters, two are still alive; Freddie Oversteegen and her sister Truus Oversteegen. The third woman, Hannie Shaft sadly lost her battle in 1945. I could go further into the details of the in-depth biographical account of the surviving sisters and the historically available information researched by Poldermans; but to experience the life of these women and girls during the horrors of that era, you really need to read this book for yourself. Fortunately, this book is available in many formats and stores. If you enjoy well researched, concisely written, biography of the horrors of war from the female perspective then this is the book you may enjoy.

Conclusion

Sophie Poldermans has provided a valuable account of the dire experiences of three young females. Their lives, and for Hannie her death, forever changed by their experiences and activities. They may have begun as ordinary students but they ended up being remarkable women. Their stories are inspirational and their bravery is undeniable. These three teenagers set a high standard for the rest of us to follow. I could not help but be inspired and motivated by the life they describe. It is a perfect memorial to the life and times of Hannie Shaft, the forgotten heroine of World War II.

Acknowledgment

My sincere thanks go to: NetGalley and the Publisher SWW Press for affording me the opportunity to review of Seducing and Killing Nazis.

https://seducingandkillingnazis.com/#home

London A-Z – REVIEW

Litercurious Book Review

London A-Z
London A-Z
TitleLondon A-Z                           
AuthorGeographer’s A-Z Map Co.      
PublisherHunter Publishing: Geographers A-Z Map Co. Ltd. (6th Ed., October 30, 2006     
FormatPaperback     
Page288     
LanguageLanguage     
ISBN #1843483289 ISBN-13 (978-1843483281)    

Author’s Bio

The Geographer’s A-Z Map is the registered author of this 6th Edition publication; a paperback, dated: 30thOctober 2006.

Who is the target audience?

Those considering studying “The Knowledge” would be the first that would come to mind when considering who would benefit from this paperback. That said anyone wanting to know how to find anything in London would be well advised to get one.

Synopsis

The London A-Z, I know her well. 

I continue to use traditional methods of locating the places I wish to travel. I find looking at a  page of the London A-Z allows me at a glance to find the path I want to take. I avoid the constant directions of an electronic voice dictating the one and only route to a destination. I live for the times I get lost and find strange and interesting locations with intriguing back stories. I am not a technophobe; in fact I am an advanced user, designer, and educator in technology related subjects. I prefer my choice of directions and those happy times where I occasionally meet people or accidentally visit places that would have been missed if I used my GPS. 

Then there is the utility of humor built into reference materials such as the London A-Z. I have been known to flip through to the index of the book and look up the funny or unusual names contained therein. These names vary from crude and lascivious names from the deep and distant past of London. Names that echo from the Saxon roots, Roman street names, and the place names inspired by the work people did at that location in times now past.  The back stories of many of the locations you can find in the index of the London A-Z can be fascinating and add to your lexicon of humorous tales or intriguing myths to discuss with those who find such matters interesting. For example there is a place called Bleeding Heart Yard, you can find it in East Central 1 (EC1). It is in Clerkenwell and is reported to be so named owing to a murder that happened there in the year 1626. It turns out however, that the woman reputed to have been murdered actually died 20 years later and not of natural causes. If you are a reader of Charles Dickens work you may recall the case; he included in his book The Little Dorrit. 

Not far from the Tower of London there is a street named Knightrider Street  (Knyghriderstrete in 1322 language). The street is named after the knights that would traverse this area from the Tower old London to Jousting tournaments in Smithfeilds. Then there is the plethora of funny, licentious, and salacious Public House and place names; for example there is Wardrobe Place in EC4. It was at this location that King Edward 3rd housed his walk-in wardrobe. Sadly, the building was destroyed in the now infamous Great Fire of London 1666. Then there is Cock Lane, EC1, a wonderful erection if I do say so myself. Cock Lane is another, all be it humorous, example of a place name that has relevance to the trade plied there in the past. Cock Lane was the only street in the City (City of London, The square mile, a private corporation) where ladies of the evening were allowed to live and work. Last but not least there is Hanging Sword Alley in EC4. In medieval times most of the country was illiterate and so there was no naming or numbering of houses, they preferred instead to use symbols. In the case of a coffee house there would often be a ladies arm holding a coffee pot. At the house on Hang Sword Lane there was a mansion and they used a hanging sword as their symbol. The area was known for fighting schools and as a rough place to visit which is probably why the Blood Bowl Alley came to be named. Again those of you familiar with Dickens work will find a reference to such places in A Tale of Two Cities in the form of Jerry Cruncher body-snatcher. 

I suggest if you are bored and in search of adventure, turn off your GPS get yourself a London A-Z and go and lose yourself for a few hours in London. Visit the places you never knew existed and perhaps find your other self.  

Always remember that a book can be much more than its cover.

Conclusion

Be it the times of Pax Romanaus or Pax Britainica always have your trusty and reliable cartographic entertainment on your person, because you never know when you’ll need the London A-Z.

Everything’s Eventual – REVIEW

Litercurious Book Reviews

Everything’s Eventual: 14 Dark Tales, Stephen King
TitleEverything’s Eventual                                             
AuthorStephen King                                         
PublisherScribner Reprint (April 17, 2018)     
FormatPaperback, Kindle, Hardcover, Audiobook           
Page464     
LanguageEnglish     
ISBN #1501197967     

Author’s Bio

The eponymous Mr. King, the author of a library of horror genre literature really needs no introduction, but just in case you spent the last 50 years on a meteor traversing the universe, I will give you the press junket introduction. Stephen King, is the child of a school teacher. It was Mrs. King who encouraged all of her children to read. Stephen King consumed literature like a man possessed. This compulsion continued through-out his life and even directed his choice of study as a young man. Whilst in academia he began writing professionally. He sold his early works for a pittance but as his skill and reputation continued, he became a much-loved horror writer of modern times. At the time of writing, Stephen King’s name is synonymous with the horror theme. Some people describe him as the King of Horror and it is hard to deny with his sky-high book sales. As this is Halloween it might be pertinent to mention that one particular story was inspired by paranormal events experienced by him and his spouse in a hotel in Colorado. King has spoken of it in the past and I encourage you to seek out his own account for more details.

Who will enjoy this collection of stories?

If you are looking for a read that disquieting, amusing at times, and frightening at others this could be a book for you this Halloween. King will take you on a sojourn into an alternative universe where things may not be as you imagine. He can take you from a hospital gurney to conversing with the Devil in the woods. Every story in this novella has something for everyone. If you aren’t a Stephen King fan already, perhaps this volume could turn you into one.

Synopsis

Everything‘s Eventual is one of many of King’s Novella’s. In my opinion, whilst this is not his greatest, it is not his worst. The series of stories span a wide gamut of characters and storylines, as you expect from a novella. What is special about this collection of stories is the expertise of the author in crafting the characters so well you can almost smell them.  The stories are so well described that you could be accompanying the characters as they transverse the plots.  One cannot help but be impressed by the sheer latitude of King’s vivid imagination. The stories are original and explore new aspects of terror. If you enjoyed King’s earlier work, such as Carrie, Salem’s Lot, or Joyland you will love this outing. My favorite of the bunch is 1408, or perhaps it is Riding the Bullet; no, it has to be Luckey Quarter.  

Conclusion

Everything’s Eventual was nearly 10 years in the coming preceded by King’s earlier novella Dreamscapes and Nightmares, and it is eminently comparable. In short, if you enjoyed the latter, you will love the former. The perfect Halloween read.

Competing in the Age of AI – REVIEW

Litercurious Book Reviews

Competing in the age of AI by By Marco Iansiti & Karim R. Lakhani  
Competing in the age of AI by By Marco Iansiti & Karim R. Lakhani        
TitleCompeting in the age of AI                                     
AuthorMarco Iansiti & Karim R. Lakhani                    
PublisherHarvard Business Review Press (January 7, 2020)     
FormatKindle, Hardcover          
Page288     
LanguageEnglish
ASIN #B07MWCTNSD     

Author’s Bio

Marco Iansiti is a Professor of Business Administration at Harvard Business School. His special expertise revolves around Technology and Operations Management. He advises Blue Chip companies globally on operational transition, and technological transformation for the 21st Century. Iansiti and Lakhani posit workable solutions and invaluable insights into the infinite utility of AI.   

I studied Managerial Cybernetics, Systems Analysis, and Systems Development under the tutelage of Stafford Beer for both my B.Sc., and M.Sc. I am currently evaluating how the synthesis of a variety of recent technologies can be applied to extend the economic potential of large distributed networks and International organizations. Much of my work includes related issues raised in Competing in The Age of AI. My experience and my academic credentials, I believe afford me a unique perspective on this manuscript.

Iansiti is a prolific author of publications based on a particular area of expertise. Some of his works include: Digital Ubiquity, The Truth About Blockchain (Iansiti & Lakhani), The Keystone Advantage (Roy Levine), and Managing Our Hub Economy. Those looking for advice on establishing digital advantage or operational model transformation of a global organization need look no further than Competing in The Age of AI. 

Karim R. Lakhani is a Business Administration Professor at Harvard Business School. Lakhani is the co-director of the Laboratory of Innovation Science at Harvard’s Institute of Quantitative Social Science, as well as the Chair of the Harvard Business School’s Analytics Program. His area of expertise is innovation and technology management. He is the author of numerous articles and case studies on technology, digital commerce, and digital innovation. He has been published in a myriad of significant publications that include: The Economist, The Wall Street Journal, and Business Week among many others.  

Who is the target audience?

This is probably the most important book on business application of digital innovations this decade. This thesis is suitable for those who want or need to understand the potential for the increased span, scope, and scale afforded by the appropriate utilization of digital innovations, particularly artificial intelligence as applied to business models. Iansiti and Lakhani’s concept provides a most important tool for Captains of industry, investors, CEOs, entrepreneurs, and students of business and technology. Iansiti and Lakhani’s publication is a must read for all those who want to improve their understanding of the application of AI in organizations. Competing in the Age of AI should be compulsory reading for all those involved in leveraging competitive advantage in the new business world underpinned by artificial intelligence.

Synopsis

The discussions herein include the question of ethics in application and distribution of technology. Iansiti and Lakhani’s have provided a map for the exploitation of the technical advances provided by new technology. The authors have given practical advice on the strengths, limitations, and challenges of employing artificial intelligence to support and augment a company’s strategy.

Conclusion

Competing in The Age of AI is a seminal work, containing all the key ingredients for global companies to explore in order to improve competitive advantage.  Iansiti and Lakhani have provided sensible, practical jargon-free explanations for the application of advanced technology strategies and advice on the potential effects on span, scope, and scale across the organization. 

Acknowledgment

My sincere thanks go to: NetGalley, and Harvard Business Review Press for affording me the opportunity to review of Competing in the Age of AI.

Halloween at litercurious

Hot Carbon – REVIEW

A Litercurious Book Review

Hot Carbon: Carbon-14 and a Volution in Science By John F. Marra
Hot Carbon By John F. Marra
Title Hot Carbon
Author James W Bancroft
Publisher Radius Book Group (April 18, 2019)
Format Hardcover
Pages 604
Language English
ISBN # 1526718014 (ISBN-13: 978-1526718013)

The Author

John F. Marra is a veteran of the U.S. Navy, and after a non-traditional route became involved in oceanographic based research. He has been studying the oceans and the effects of carbon 14 for over 30 years.

Even though he was a Chicago boy, he had a strong desire to sail the seas, eventually becoming a Naval Officer. The sea wasn’t his only calling however, and being the possessor of a sharp mind, he developed a keen interest in nature and the natural world in general. Marra eventually resigned his commission to study in a graduate program as a research assistant. His CV is resplendent with many long years of oceanographic research. He moved to a more academic track and has enjoyed success in his field. He is currently a Professor and Director of AREAC Earth and Environmental Sciences at Brooklyn College.

Find out more about John Marra here: http://www.brooklyn.cuny.edu/web/academics/faculty/faculty_profile.jsp?faculty=662

Who would enjoy this book?

This volume would appeal most to those with a scientific focus. Students of the Environmental Sciences would be the best candidates to enjoy the offering in Hot Carbon. I studied a different scientific profession, and yet, I still found this first outing by Marra to be entertaining and enlightening, although replete with factual errors. If you have an interest in learning new things, this book will be an exciting read. Almost, anyone over 16 years old will find this a useful addition to their bookshelf.

What is the story about?

The bulk of the book revolves around Carbon 14 and its universal ubiquity. Marra explains, in lucid and concise terms, the importance of the isotope and its unique importance to life on earth as it corresponds to the process of photosynthesis and its interaction with microscopic phytoplankton. The book is beautifully illustrated with a plethora of images, maps, charts, and tables.

From the inception, I found the book particularly delightful and entertaining; two responses I don’t usually get from what I thought was a hardcore science thesis. In the first few pages you are left in no doubt of Marra’s dedication to his work as he describes the privations on one of his many research trips. He effectively depicts the myriad of dangers and the deadly nature of the job. For a brief moment, I believed that I was reading an adventure book, rather than what could have been a stultifying stuffy re-telling of some mediocre scientific research. I was hooked on the book and couldn’t wait to finish.

I was particularly struck by the understated delivery of the prose. His descriptions, explanations, and familiarity with the subject really sold the story and highlighted his abilities as a professor. It was an easier read than expected and that added to its allure. I was disappointed when the book ended; it left me wanting more. I understand that this is Marra’s first book and I hope it won’t be his last. I will certainly be pre-ordering his next publication. So please John, don’t keep us waiting.

Conclusion

There are areas where those who didn’t pay attention in organic chemistry may get a little lost in the translation of detailed processes, but it’s not a deal breaker in any way.

Overall, I found this volume to be a pleasure to read, easily accessible, and well written. You don’t have to be a scientist to enjoy this book. Put simply, you don’t want to be the one person in class not to have read this; don’t be that guy!

Acknowledgements

I wish to extend my kindest regards to The Author, The Publisher, and NetGalley for giving me the opportunity to review this wonderful book.

The Mosquito – REVIEW

A Litercurious Book Review

Mosquito: A Human History of Our Deadliest Predator, Timothy C. Winegard
Mosquito by Timothy Winegard
Title The Mosquito: A Human History of Our Deadliest
Predator
Author Timothy C. Winegard
Publisher Penguin Group Dutton, 1st Edition (August 6, 2019)
Format Kindle, Paperback, Hardcover, Audiobook
Pages 496
Language English
ISBN # 1524743410 (ISBN-13: 978-1524743413)

About the Author:

Dr. Timothy C. Winegard is a military historian who graduated from Oxford University with a PhD and is currently a professor of history and political science at Colorado Mesa University. He is best known for his works on military history however, he has written on the subject of indigenous studies. Before becoming a best-selling writer, Dr. Winegard worked as a military officer with his native Canadians and later the British forces. He is a  sports fan and stalwart supporter of his favorite teams: the Detroit Lions and the Detroit Red Wings. Despite his busy schedule, the good doctor likes to spend his down time with his family at home.

Who is the target audience?

If you gravitate to the nonfiction, history, evolution, or similar shelves in your local bookshop, you may enjoy the exquisite prose and comprehensive research in The MosquitoA Human History of Our Deadliest Predator.  

What is this book about?

The story of The Mosquito spans thousands of years beginning with the evolution of the insect that plagues our lives to this day. Dr. Winegard’s writing style is reminiscent of Guns, Germs, and Steel or even a Simon Winchester.  The focus of the book is the intimate relationship that mosquitos and humans have shared over time, and the impact on humanities antiquity and on its future. The book is abundant in superlative research and in witty humor. By the end of the book you will be in no doubt as to the destruction this tiny insect has wrought across the human world throughout history. You will learn a plethora of facts and information through a skillful scientific style of writing. Timothy gives you the big picture, a map of the problem that allows you to trace the changes to human existence shaped by the illnesses spread by one of our most dangerous predators. 

Conclusion:

The Mosquito: A Human History of Our Deadliest Predator, By Timothy C. Winegard is a masterfully written book, being both fascinating and funny. Mosquito is jam packed with in-depth and informed research. It is epic in its breadth, and chronicled with skill. Ultimately, the book is infinitely entertaining, educational, and surprising at times. The book does prompt the thought that humanity believes itself to be top of the food chain, but are we really when such a tiny combatant can wreak such havoc? 

I would like to take this opportunity to thank the following: Penguin Group Dutton, Dr. Timothy C. Winegard, and NetGalley for allowing me to review this book.

How To Bake Pi – REVIEW

A Litercurious Book Review

How to Bake Pi: An Edible Exploration of The Mathematics of Mathematics, Eugenia Cheng
How to Bake Pi by Eugenia Cheng
Title How To Bake Pi
Author Eugenia Cheng
Publisher Basic Books (May 5, 2015)
Format Kindle, Audiobook, Hardback, Paperback
Pages 300
Language English
ISBN # 0465097677 (ISBN-13: 978-0465097678)

Who is Eugenia Cheng?

Eugenia Loh-Gene Cheng is a British mathematician who specializes in a fringe area of mathematics referred to as Higher-Dimensional Category Theory. She is also known for her support of popular mathematics. Among her many publications are The Art of Logic and, my personal favorite, Beyond Infinity. Professor Cheng attended school at Roedean and is a graduate of The University of Cambridge with her Thesis: Higher-dimensional category theory: opetopic foundations (2002). She graduated with both a BA and a PhD.

Who is the target audience?

This book could appeal to anyone; perhaps with the exception of those traumatized by ill intentioned or professionally inept math teachers. Eugenia has taken the everyday practice of baking and uses it as frame to hang mathematical theories on, to make the mathematics more accessible to a wider audience, and to simplify the theory for the common man. These theories are not new concepts, however, they may be fresh concepts to you. It is a skillfully woven discourse with Category Theory at its heart. Of course there may be some people who will not understand the basic concepts, but I believe the majority of people who read this book will learn something that may benefit them.

In this book

Having read How to Bake Pi, I’ve noted the Professor is a skilled and gifted educator. She takes the art of teaching mathematics to a whole new level. Her ability to enlighten the audience is due in part to her: familiarity with her subject, and her varied methods to demystify the subject; while simultaneously encouraging an enthusiasm for math that most people never knew they had.

I enjoyed the humor and the lucidity of her delivery. The mathematical logic is there throughout the text, but it is softened through: clear, lucid, and work-a-day explanations that aid the reader in exploring the world of math.

Conclusion

I found this book to be engaging, warm, effusive, and fun. Ultimately, Eugenia has proven that it isn’t what you teach, but how you teach that makes the difference.

Acknowledgements 

Thanks to the following: NetGalley, Basic Books, and Eugenia Cheng.

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